35x12.50R20's on stock wheels
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#5
35's will affect your towing. If you do a lot of heavy towing/hauling, I'd stick with a 33 inch tall tire if you do not want to regear. Also, some fitment problems occur using the OEM 20's because of the backspacing on the wheel. Some members report that some 12.50 inch wide tires, especially those with aggressive sidewall lugs, will touch the upper control arm/ball joint.
#6
Wandell is right. I tried a 35x12.5x20 Mud grappler a couple weeks ago and it touched the upper control arm as soon as I put it on, and that was with a 1/4" spacer. I've seen plenty run the toyo m/ts with 20's and no major problems, but it seems like they would hit on my truck. I am looking at the nitto trail grappler 295/65/20.